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THE ABC OF TISSUE ENGINEERING SCAFFOLD DESIGN (Larry Hench Memorial Lecture)

28 November 2019 18:30-20:30, London , United Kingdom


Introduction
6:30pm start, followed by networking and refreshments at 7:30pm.

For many years, there has been interest in the use of biomaterials to replace human tissues damaged by injury or disease.  Over time, the materials of choice have gradually changed from those that simply offer mechanical support to those that interact directly with the biological environment. Focus is now on the recruitment and delivery of biological cells to assist in the repair process. With this move from tissue replacement to cell-mediated tissue reconstruction and regeneration (or tissue engineering), there is increasing need for the design of optimised, porous biomaterial structures – often referred to as “Scaffolds”. By first understanding the nature of the tissues that we want to regenerate, it is possible to address the requirements for particular clinical applications.

This talk will consider two scaffold materials: collagen, a highly versatile and bioactive natural macromolecule; and hydroxyapatite, a calcium phosphate material similar in composition to bone mineral. To optimise tissue repair processes, it is important to understand the influence on cell behaviour of the structure of the scaffold, and the interconnections between the pores within them. Choice of scaffold surface chemistry also allows us to balance scaffold “activity” and mechanical performance. There is also a need to consider an appropriate testing environment to mimic the cellular interactions which take place within the body.

The 2019-20 June Wilson Award, offers a cash prize to support the work of female scientists and engineers based in a research institution and/or (commercial/non-profit) organisation in the South East of England, who has demonstrated excellence in the area of materials science and engineering.

The June Wilson award is open to individuals below the age of 30 or within a maximum of 5 years after their first research degree.

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Imperial College London

Room LT 664 , Imperial College London, City and Guilds Building, Imperial College London, Kensington, London , SW7 1AL, United Kingdom

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