The meeting will bring together leading scientists from the "OMICS” field with leading structural and cell biologists, for the main purpose of discussing scientific issues arising at the interface of these complementary fields. The general aim of the symposium is to explore the possible synergisms and cross-talk between the large-scale and classical approaches to biological networks and review/investigate possible avenue to more generally populate current networks with dynamics and mechanistic insights that will ensure high levels of biological understanding and contributes deciphering fundamental principles.