ࡱ> %` VbjbjNN ),,H ***8bL<+    ++-+-+-+-+-+-+$-h/Q+<"<<Q+  f+###<  *6#<++##:(,)  &<* ( *\|+0+) 0Z!0)0)X#%9Q+Q+! +<<<<d ** The ŷAV Industrial Affairs Division 21st Symposium on Medicinal Chemistry in Eastern England Thursday 29th April 2010, Fielder Centre, University of Hertfordshire Organising Committee: Dr A Faller (Eli Lilly), Dr N Hamblin (GlaxoSmithKline) MORNING PROGRAMME Chairman: Dr Alan Brown (Pfizer) The Discovery and Synthesis of a Series of Octahydropyrrolo[3,4-c] pyrrole Based Selective Histamine H4 Receptor Antagonists Charlotte Lane (Pfizer) Selective Muscarinic M1 Agonists: A Novel Treatment for Cognitive Disorders Dale Johnson (GlaxoSmithKline) Medchem, Metrics and Meaning: Assessing Medicinal Chemistry Progress and Quality in Cancer Drug Discovery Projects Rob Bradbury (Astra Zeneca) AFTERNOON PROGRAMME Chairman: Prof Robin Ganellin (University College London) Capps-Green-Zamoya Award Presentation Discovery of Small Molecule Inhibitors of Fatty Acid Amide Hydrolase Stephen Roughley (Vernalis) Sitting on a Goldmine: Knowledge Based Design of 5-HT2b Antagonists David Hirst (GlaxoSmithKline) Optimum Lipophilicity and Compound Quality -Strategies and Consequences for Lead Optimisation Mike Waring (AstraZeneca) Discovery of NERI IV. A Novel, Selective Norepinephrine re-uptake Inhibitor Magnus Walter (Eli Lilly) HSP 90 - From Fragment to Clinic Gianni Chessari (Astex) For further information contact: Dr A.Faller Eli Lilly & Co Ltd, Lilly Research Centre, Erl Wood Manor, Sunninghill Rd, Windlesham, Surrey, GU20 6PH Tel: 01276 483036. e-mail: HYPERLINK "mailto:faller_andrew@Lilly.com"faller_andrew@Lilly.com 21st SYMPOSIUM ON MEDICINAL CHEMISTRY IN EASTERN ENGLAND Organised by the Biological and Medicinal Chemistry Sector of the ŷAV Industrial Affairs Division 29th April 2010 Fielder Centre, University of Hertfordshire, Hatfield, Hertfordshire, UK REGISTRATION FORM Fees, including lunch: ŷAV Members: 75 ( Non-Members: 90 ( Students/Retired Members Free ( Please tick appropriate box and enclose cheque payable to "ŷAV-BMCS" SURNAME ......................... FIRST NAME ..................... TITLE ........... AFFILIATION .......................................................................... ADDRESS .................................................................................. .................................................................................................... E-MAIL ADDRESS PLEASE RETURN FORMS (NOT LATER THAN APRIL 19th 2010) TO: Dr A. 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