It is estimated that 30% of diseases caused by mutations can be linked to splicing. Mutation of a splice site can result in site loss of function and specificity, causing insertion or deletion of amino acids or disrupting the reading frame. The importance of understanding and properly decoding roles governing splicing have become a fact for the research community, as demonstrated by the increasing number of manuscripts devoted to this subject. Splicing 2023 intends to join a friendly academic environment, all of us working or interested in moving to this area of research. The conference will take place in summer in one of the best beach areas in Portugal, the sea village of Caparica (South Lisbon area). We aim to present your latest results in Splicing and join the best researchers in this area of knowledge. Please do not hesitate to contact me if you have any suggestions to help us make this event remarkable.